paper52

Deep Eutectic Solvent as a Recyclable Catalyst for

Three-Component Synthesis of b-Amino Carbonyls

Fariba Keshavarzipour • Hossein Tavakol

Catal Lett (2015) 145:1062–1066

Abstract

We have reported one-pot, three-component

Mannich type reaction of aldehyde, amines and ketone

(acetone and acetophenones), catalyzed by deep eutectic

solvent (choline chloride/zinc chloride) at room temperature

to give b-amino carbonyls in good yields. The catalyst

could be recycled at least four times without remarkable

decrease in its catalytic activity. The general method is

easy, fast and environmental friendly.

Search form