CuI-catalyzed, one-pot synthesis of 3-aminobenzofurans in deep eutectic solvents
Appl Organomet Chem. 2021;35:e6433.Bahareh Abtahi, Hossein Tavakol Abstract An environmentally friendly method is presented here for the synthesis of various benzofuran derivatives using CuI catalyst. In this line, a one-pot, 3-component reaction of alkynes, different aldehydes, and amines is employed in choline chloride-ethylene glycol deep eutectic solvent as an available, cheap, and green media. The employed method includes easy workup and good yields. In this work, 12 different benzofuran derivatives have been prepared in 7 h at 80°C.